If you want to take advantage of the power of multi-core machines, you need to start creating applications with parallel processing using PLINQ, the Task Parallel Library and the new features of Visual Studio 2010.
The new IntelliTrace feature in Visual Studio 2010 promises to eliminate the pernicious scourge of "no repro" bugs by giving developers a detailed view of what happened during execution when a bug was filed. Here's how you can get started with IntelliTrace.